
WELCOME
ShapingShaping
thethe
FutureFuture
ofof
MentalMental
Health.Health.
Palo Santo invests in next-generation neuroscience companies developing breakthrough therapeutics and technologies for mental health.
THE TIME IS NOW
Transforming Mental Health
Through Next-Generation
Neuroscience Targets and
Psychedelic Therapeutics
LEARN WHYThrough Next-Generation
Neuroscience Targets and
Psychedelic Therapeutics
23
Core investments
23 core investments across neuroscience therapeutics and technologies


12
Strategic
Biopharma
Partnerships
Biopharma
Partnerships
Partnerships across leading pharmaceutical and biotechnology companies, including AbbVie's $1.2B acquisition of Gilgamesh's lead program
08
FDA Breakthrough Therapy Designations
Eight FDA Breakthrough Therapy Designations in psychedelic medicine
350+
Clinical Trials
Over 350 FDA clinical trials involving psychedelics in progress worldwide
23
Core investments
23 core investments across neuroscience therapeutics and technologies


12
Strategic Biopharma Partnerships
Partnerships across leading pharmaceutical and biotechnology companies, including AbbVie's $1.2B acquisition of Gilgamesh's lead program
08
Breakthrough Therapy Designations
Eight FDA Breakthrough Therapy Designations in psychedelic medicine
350+
Clinical Trials
Over 350 FDA clinical trials involving psychedelics in progress worldwide

Portfolio.
From next-generation psychedelics to novel CNS targets and enabling technologies, our portfolio spans the forefront of neuroscience innovation driving new treatments for mental health


Building the Future Of Brain Health with AI-Driven Neurotechnology
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Helping Patients with Neurological & Psychiatric Disorders through Innovative Psychedelic Pharmaceuticals.
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Novel Psychedelic Analogues For the Treatment of Neuropsychiatric Conditions
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Revolutionizing short-duration psychedelic therapies for underserved medical conditions
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Reimagining brain health through new insights into synaptic biology
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Full Portfolio
Full Portfolio